AKEMI TOMODA, MD, PHD

Harvard title(s): Visiting Assistant Professor in Psychiatry, Department of Psychiatry of Harvard Medical School
Email: atomoda@mclean.harvard.edu
Telephone: (617) 855-2991
Fax: (617) 855-3712
Office Address: Developmental Biopsychiatry Research Program
Clinical Interests:
Dr. Tomoda is a member of the following societies:
- The Society for Neuroscience
- The American association for Chronic Fatigue Syndrome
- The Society for International Conference of Psychosomatic Medicine
- The Society for American Academy of Child & Adolescent Psychiatry
- The American association for Biological Psychiatry
- The Japanese society for Pediatrics
- The Japanese society for Child Neurology
- The Japanese society for Chronobiology
Curriculum vitæ: (PDF format)
Publications:
1. Tomoda A, Jhodoi T, Rabab EM, et al. Cytokine production and modulation: Comparison of chronic fatigue syndrome (CFS) patients and normal controls. Psychiatric Research 2005; 134: 101-104.
2. Takimoto M*, Hamada A*, Tomoda A*, Ohdo S*, Ohmura T, Sakato H, Kawatani J, Jodoi T, Nakagawa H, Terazono H, Koyanagi S Higuchi S, Kimura M, Tukikawa H, Irie S, Saito H, Miike T. (*These authors contributed equally to this study.) Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder. AM J PHYSIOL-REG I (AJP-Regulatory, Integrative and Comparative Physiology) 2005 in press.
3. Teicher MH, Samson J, Tomoda A, Ashy M, SL Andersen. Neurobiological and behavioral consequences of exposure to childhood traumatic stress. Textbook of Stress: Bengt B. Arnetz and Rolf Ekman, Editors, 2005 (in press).
4. Hosoya M, Mori S, Tomoda A, et al. Pharmacokinetics and effects of ribavirin following intraventricular administration for treatment of subacute sclerosing panencephalitis. Antimicrobial Agents and Chemotherapy 2004; 48: 4631−4635.
5. Miike T, Tomoda A, Jhodoi T. Learning and memorization impairment in childhood chronic fatigue syndrome manifesting as school phobia in Japan. Brain Dev. 2004 26:442-447.
6. Tomoda A. Reply "Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan" Brain Dev 2003; 26:514.
7. Tomoda A, Nomura K, Shiraishi S, Hosoya M, Hamada A, Ohmura T, Hosoya M, Miike T, et al. Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis SSPE in Japan. Brain Dev 2003; 25:514-7.
8. Tomoda A, Jhodoi T, Kawatani J, Hamada A, Ohmura T, Tonooka S, Miike T. Differences in human Per2 gene expression, body temperature, cortisol and melatonin parameters in remission and hypersomnia in a patient with recurrent hypersomnia. Chronobiol Int, 20, 891-898, 2003.
9. Hara S, Kimura H, Hoshino Y, Hayashi N, Negoro T, Okumura A, Kajita Y, Sakuma T, Nakayama T, Hosoya M, Tomoda A, Morishima T. Combination therapy with intraventricular interferon-a and ribavirin for subacute sclerosing panencephalitis and monitoring measles virus RNA by quantitative PCR assay. Brain Dev 25:367-369, 2003
10. Miike T, Tomoda A, Jhodoi T, Iwatani N, Mabe H. Learning and memorization impairment in childhood chronic fatigue syndrome manifesting as school phobia in Japan. Brain Dev 13; 266-269, 2003.
11. Tomoda A, Jhodoi T, Miike T. Chronic fatigue and abnormal biological rhythms in school children. JCFS, 60: 607-612, 2001.
12. Tomoda A, Shiraishi S, Hosoya M, Hamada A, Miike T. Combined treatment with interferon-and ribavirin for subacute sclerosing panencephalitis (SSPE). Pediatr Neurol 24: 54-59, 2001.
13. Ninomiya T, Iwatani N, Tomoda A, Miike T. Effects of exogenous melatonin on the serum levels of pituitary hormones in humans. Clin Physiol 21; 292-299, 2001.
14. Hosoya M, Shigeta S, Mori S, Tomoda A, Shiraishi S, Miike T, Suzuki H. High dose intravenous ribavirin therapy for subacute sclerosing panencephalitis (SSPE). Antimicrob Agents Ch 45; 943-945, 2001.
15. Matsui M, Ito M, Tomoda A, Miike T. Complex regional pain syndrome in childhood: report of three cases. Brain Dev 22; 445-448, 2000.
16. Tomoda A, Miike T, Yamada Y, Ogawa M, Honda H, Moroi T, Ohtani Y, Morishita S. Chronic fatigue syndrome (CFS) in childhood. Brain Dev 22: 60-64, 2000.
17. Tomoda A, Miike T, Iwatani N, Ninomiya T, Mabe H, Kageshita T, Ito S. Effect of long-term melatonin administration on school-phobic children and adolescents with sleep disturbances. Curr Ther Res 60; 607-612, 1999.
18. Furusawa M, Morishita S, Kira M,Takahashi M, Tomoda A, Miike T, Arai N. Evaluation of school refusal with localized proton MR spectroscopy. Asia Ocean J Radiol 3; 170-174, 1998.
19. Tomoda A, Miike T, Yonamine K, Adachi K, Shiraishi S.　Disturbed circadian core body temperature rhythm and sleep disturbance in school refusal children and adolescents. Biol Psychiatry 41; 810-813, 1997.
20. Tomoda A, Miike T, Miyagawa S, Negi A, Takeshima H.　Subacute sclerosing panencephalitis and chorioretinitis. Brain Dev 19; 55-57, 1997.
21. Koide R, Onodera O, Ikeuchi T, Kondo R, Tanaka H, Tomoda A, Miike T.　Atrophy of the cerebellum and brainstem in dentatorubral-pallidoluysian atrophy (DRPLA): Influence of CAG repeat size on MRI findings. Neurology, 49:1605-1612, 1997.
22. Iwatani N, Miike T, Kai Y, Kodama M, Mabe H, Tomoda A.　Glucoregulatory disorders in school refusal students. Clin Endocrinol 47; 273-278, 1997.
23. Ikeuchi T, Koide R, Tanaka H, Onodera O, Igarashi S, Takahashi H, Kondo R, Ishikawa A, Tomoda A, Miike T, Shimizu N, Ikuta F, Tsuji S. Dentatorubral-pallidoluysian atrophy (DRPLA): Clinical features are closely related to unstable expansions of CAG repeat. Ann Neurol 37; 769-775, 1995.
24. Tomoda A, Miike T, Honda T, Fukuda K, Kai Y, Nabeshima M, Takahashi M. Single-photon emission computed tomographiy for cerebral blood flow in school phobias. Curr Ther Res 56; 1088-1093, 1995.
25. Koide R, Ikeuchi T, Tanaka H, Onodera O, Igarashi S, Endo K,Takahashi H, Kondo R, Ishikawa A, Tomoda A, Miike T, Naito H, Ikuta F, Tsuji S. Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nat Genet 6; 9-13, 1994.
26. Tomoda A, Miike T, Matsukura M. Circadian rhythm abnormalities in adrenoleukodystrophy and methyl B12 treatment. Brain Dev 17; 428-431, 1995.
27. Tomoda A, Miike T, Uezono K, Kawasaki T. A school refusal case with biological rhythm disturbance and melatonin therapy. Brain Dev 16; 71-76, 1994.
28. Tomoda A, Zhao J, Ohtani Y, Miike T, Uchino M, Higuchi I. Two patients with distal muscular dystrophy and autonomic dysfunction. Brain Dev 16; 65-70, 1994.
29. Ohtani Y, Tomoda A, Miike T, Matsukura M, Miyatake M, Narazaki O. Central nervous system disorders and possible brain type carnitine palmitoyltransferase II deficiency. Brain Dev 16; 139-145, 1994.
30. Tomoda A, Ikezawa M, Ohtani Y, Miike T, Kumamoto T. Progressive myoclonus epilepsy: Dentato-rubro-pallido-luysian atrophy (DRPLA) in childhood. Brain Dev 13; 266-269, 1991.