CHUN-HYUNG KIM, PHD
- McLean title(s): Instructor
- Email: chkim@mclean.harvard.edu
- Telephone: (617) 855-2026
- Fax: 617-855-3479
- Office Address: Molecular Neurobiology Laboratory, Mail Stop 149
- Degree(s): B.Sc.1985, M.S. 1988, Ph.D. 2001
- Clinical Interests:
Early genetic diagnosis, development of new drug targets for PD, and novel therapeutic approaches for norepinephrine-related disorders.
- Bio: Chun-Hyung Kim received his B.Sc. and M.S. in Food Microbiology from Seoul National University. He earned his PhD in Anatomy and Neurobiology at Tennessee University in 2001. He worked at LG Life Science in Korea as a Principal Research Scientist. He joined the Molecular Neurobiology Laboratory in 2003.
- Publications: (Selected)
- Kim, C.H., Hwang, D.Y., Park, J.J. and Kim, K.S. (2002) Multiple interactions between transcription factors including HoxA5 and Phox2 proteins at a proximal promoter domain critically regulate the noradrenergic cell type-specific transcriptional activity of the human norepinephrine transporter gene. J. Neuroscience. 22, 2579-2589
- Kim, C.H., Hahn, M., Joung, Y.S., Anderson, S.L., Steele, A.H., Gizer I., Teicher, M.H., Cohen, B.M., Robertson, D., Waldman, I.D., Blakely, R. and Kim, K.S. (2006) A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder. Proc. Natl. Acad. Sci. 103, 19164-19169.
- Kim, C.H., Waldman, I.D., Blakely, R. and Kim, K.S. (2008) Functional gene variations in the Human Norepinephrine Transporter: Association with Attention Deficit/Hyperactivity Disorder. The New York Academy of Science 1129:256-260.
- *Kim D, *Kim C.H., Moon JI, Chung YG, Chang MY, Han BS, Ko S, Yang E, Cha KY, Lanza R, Kim KS. (2009) Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell. 4(6):472-476. (* co-first author)
- *Kim C.H., Leung A., Huh Y.H., Yang E., Kim D.J., Leblanc P., Ryu H., Kim K., Kim D.W., Garland E.M., Raj S.R., Biaggioni I., Robertson D., and *Kim K.S. (2011) Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine b-hydroxylase. J Biol Chem, 286(11): 9196. (*co-corresponding author)
