EDWARD G. MELONI, PHD
- Harvard title(s): Assistant Professor of Psychiatry
- McLean title(s): Kaneb Fellow in Psychiatry
- Email: emeloni@mclean.harvard.edu
- Telephone: (617) 855-2064
- Fax: (617) 855-3835
- Office Address: Behavioral Genetics Laboratory and and Medicinal Discovery and Development
- Degree(s): Edward Meloni received his Ph.D. in Neuroscience from Yale University ('00).
- Clinical Interests: His work is focused on bipolar disorder with the aim of 1) a better understanding of the neurobiology of this psychiatric illness, 2) developing better animal models of this disease, and 3) discovering and developing better medications for the treatment of bipolar disorder. The scope of the research includes analyses at the molecular, cellular, and behavioral level to address these specific aims. Thanks to the generous support of the Stanley Foundation, it is the goal of the MDDL to make a significant contribution to the treatment of bipolar disorder.
- Bio: Edward is an Instructor in the Medicine Discovery and Development Laboratory (MDDL). Before joining the staff at McLean Hospital, Edward's post-doctoral experience included research in the Psychiatry Department at Emory University and Neurology Department at Harvard University.
- Publications:
- PubMed search for Meloni EG[au]
- Meloni EG, Davis M (1999) Muscimol infused into the deep layers of the superior colliculus/mesencephalic reticular formation blocks expression but not acquisition of fear-potentiated startle in rats. Behav Neurosci 113: 1-9.
- Meloni EG, Davis M (2000) GABA in
the deep layers of the superior colliculus mediates
the enhancement of startle by the dopamine D1 receptor
agonist SKF 82958. J Neurosci, 201: 5374-5381.
- Meloni EG, Davis M (2000) Enhancement
of the acoustic startle response by dopamine agonists
after 6-hydroxydopamine lesions of the substantia nigra
pars compacta: corresponding changes in c-Fos expression
in the caudate-putamen. Brain Res, 879: 93-104.
- Meloni EG, Davis M (2000) Synergistic
enhancement of the acoustic startle reflex by dopamine
D1 and 5-HT1A agonists and corresponding changes in
c-Fos expression in the dorsal raphe of rats. Psychopharmacology,
151; 359-367.
