JOHN W. MUSCHAMP, PHD
- McLean title(s): Postdoctoral Fellow
- Email: jmuschamp@mclean.harvard.edu
- Telephone: (617) 855-2329
- Fax: (617) 855-2023
- Office Address: MRC 215-H
- Degree(s): John received his B.A. in Psychology from Gettysburg College in 2001, his M.A. in Behavioral Neuroscience from the State University of New York at Buffalo in 2005, and his Ph.D. in Neuroscience from Florida State University in 2007.
- Bio: John is interested in the neurobiology of affect and motivated behavior as it relates to mood disorder and addiction. His doctoral work focused on natural reinforcers and how hypothalamic peptides may convey behaviorally-relevant endocrine signals to brain reward systems. At the Behavioral Genetics Laboratory, John continues to examine the regulation of brain reward pathways by neuropeptides and other gene products, with the aim of developing novel treatments for depression and substance abuse. His work has been supported by a Kirschstein National Research Service Award from the National Institute of Mental Health.
- Publications:
- Muschamp JW, Dominguez JM, Sato SM, Shen RY, Hull EM (2007) A role for hypocretin (orexin) in male sexual behavior. J Neurosci 27: 2837-45
- Hull EM, Dominguez JM, Muschamp JW (2007) Neurochemistry of male sexual behavior. In: Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry and Neuroendocrinology (3rd ed.), Lajtha A and Blaustein J, Eds. Springer-Verlag, New York
- Fong PP, Olex AL, Farrell JE, Majchrzak RM, Muschamp JW (2005) Induction of preputium eversion by peptides, serotonin antagonists, and selective serotonin reuptake inhibitors in Biophalaria glabrata. Invertebrate Biol 124: 296-302
- Lagoda G, Muschamp JW, Vigdorchik A, Hull EM (2004) A nitric oxide synthesis inhibitor in the medial preoptic area inhibits copulation and stimulus sensitization in male rats. Behav Neurosci 118: 1317-23
- Hull EM, Muschamp JW, Sato S (2004) Dopamine and serotonin: Influences on male sexual behavior. Physiol Behav 83: 291-307
- Muschamp JW, Regina MJ, Hull EM, Winter JC, Rabin RA (2004) Lysergic acid diethylamide and [-]-2,5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex. Brain Res 1023: 134-40
- Dominguez JM, Muschamp JW, Schmich JM, Hull EM (2004) Nitric oxide mediates glutamate-evoked dopamine release in the medial preoptic area. Neurosci 125: 203-103
- Muschamp JW, Siviy SM (2002) Behavioral sensitization to amphetamine follows chronic administration of the CB1 agonist WIN 55,212-2 in Lewis rats. Pharmacol Biochem Behav 73: 835-42