PIERRE R. LEBLANC, PHD
- McLean title(s): Consultant
- Email: pleblanc@partners.org
- Telephone: 617-643-7134
- Fax: 617-855-3479
- Office Address: Molecular Neurobiology Laboratory, Mail Stop 149
- Degree(s): B.Sc. 1979, Ph.D. 1991
- Clinical Interests: The development of mitigating agents against radiation induced lung injury, cancer immunotherapy, fugetaxis and assay development.
- Bio: Pierre Leblanc joined Dr. Kim's laboratory in 2004 as a consultant on the development of antibodies against selected neuro targets. He received a B.Sc. in Biochemistry from McGill University and pursued graduate studies at McMaster University where he received a Ph.D. in Biochemistry studying membranes biogenesis. For his post-doctoral work he first joined the laboratory of Dr. David Raulet at the Massachusetts Institute of Technology studying cellular and molecular immunology focusing on the gamma/delta T-cell receptor rearrangements. Later he joined the laboratory of Syamal Datta at Tufts University Medical School studying pathogenic Vb T-cell receptor usage in a mouse model of SLE. As a staff scientist at Boston University Medical Center, Pierre studied the immunoglobulin repertoire of individuals infected with HIV. From 1996 to 2004, Pierre held several positions in industry focusing on antibody product development and assay development. In 2005 he joined the Center for Integration of Medicine & Innovative Technology (CIMIT) at the Massachusetts General Hospital as a senior scientist studying biological weapons defense and in immunomodulators.
- Publications: (Selected)
- Kim, C.-H., Leung, A., Huh, Y. H., Yang, E., Kim, D.-J., Leblanc, P., Ryu, H., Kim, K., Kim, D.-W., Garland, E. M., Raj, S. R., Biaggioni, I., Robertson, D., and Kim, K.-S. (2011) Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine beta-hydroxylase., Journal of Biological Chemistry 286, 9196-9204.
- Santosuosso, M., Righi, E., Hill, E. D., Leblanc, P. R., Kodish, B., Mylvaganam, H. N., Siddappa, N. B., Stevceva, L., Hu, S.-L., Ghebremichael, M., Chenine, A.-L., Hovav, A.-H., Ruprecht, R. M., and Poznansky, M. C. (2011) R5-SHIV Induces Multiple Defects in T Cell Function during Early Infection of Rhesus Macaques Including Accumulation of T Reg Cells in Lymph Nodes., PLoS ONE 6, e18465.
- Huh, Y., Oh, M. S., Leblanc, P., and Kim, K.-S. (2010) Gene transfer in the nervous system and implications for transsynaptic neuronal tracing., Expert opinion on biological therapy 10, 763-772.
Updated: 01.2012
