RAKESH KARMACHARYA, MD, PHD
- Harvard title(s): Assistant Professor in Psychiatry
- McLean title(s): Medical Director, Schizophrenia and Bipolar Disorder Research Clinic
- MGH title(s): Director of Stem Cell Research, Center for Human Genetic Research - CEDD/PNGU
- Email: karmacharya@mcb.harvard.edu
- Telephone: 617-855-3947
- Fax: 617-855-2895
- Office Address: Schizophrenia and Bipolar Disorders Program
McLean Hospital, 115 Mill St, Belmont, MA 02478
- Degree(s):
- 1993 A.B. with honors, Biochemical Sciences, Harvard University, Cambridge, Massachusetts
- 1994 M.S. Molecular Biophysics & Biochemistry, Yale University, New Haven, Connecticut
- 2002 M.D., Ph.D. in Biophysics with honors, Albert Einstein College of Medicine, Bronx, New York
- 2009 M.M.Sc., Harvard Medical School, Boston, Massachusetts
- Residency:
- 2002 - 2003 Resident, Internal Medicine, Massachusetts General Hospital
- 2003 - 2006 Resident, Psychiatry, Massachusetts General Hospital & McLean Hospital
- 2005 - 2006 Chief Resident, Schizophrenia & Bipolar Disorder Program, McLean Hospital
- 2006 - Present Physician-Scientist, Chemical Biology Program, Broad Institute
of Harvard and MIT
- Board Certifications(s):
- 2004 Full license, Commonwealth of Massachusetts Board of Registration in Medicine
- 2007 Diplomate, American Board of Psychiatry & Neurology
- Bio: His research focuses on applying chemical biology approaches to the study of cellular processes relevant to the pathogenesis and treatment of schizophrenia and bipolar disorder. He is studying novel mechanisms that underlie the stability of beta-catenin in the Wnt signaling pathway, which is a pathway of interest in the treatment of bipolar disorder. He is also creating induced pluripotent stem (iPS) cells using fibroblasts from patients with schizophrenia and bipolar disorder, with the goal of investigating the disease biology in live neuronal cells with the patients' genetic makeup.
Updated: 11.2011
