CLINICAL UNIT BASED RESEARCH
CPDD 2008 Annual Meeting. San Juan Puerto Rico
41 ADOLESCENTS WITH ATTENTION DEFICIT DISORDER AND CO-OCCURRING SUBSTANCE USE DISORDERS: REFERRAL SOURCES AND RECRUITMENT IN A MULTI-SITE CLINICAL TRlAL
G. Bailey 3, W. Jaffee 1, R. Weiss 1, M. Lohman 2 and P. Riggs 2,
1 ADATP, Harvard Medical School, McLean Hospital, Belmont, MA, 2 Psychiatry, University of Colorado School of Medicine, Denver, CO and 3 Stanley Street Treatment and Resources, Fall River, MA
Aims: Limited clinical research in adolescents with co-occurring substance use and psychiatric disorders has impeded development of evidence-based treatment guidelines. The aim of this report is to identify productive referral sources and methods of recruiting these adolescents for research. Methods: Data were collected from the initial 302 consented and 195 randomized participants in the National Institute on Drug Abuse' Clinical Trials Network's Randomized Controlled Trial of Osmotic-Release Methylphenidate for Attention Deficit Hyperactivity Disorder in Adolescents with Substance Use Disorders. 11 participating substance treatment clinics were encouraged to recruit from usual patient referral sources and to establish new referral sources. Results: Across demographic groups and sites the largest referral source has been study clinics themselves (49.3% of total participants consented; 48.7% of total participants randomized) followed by juvenile justice (10.6% consented, 108% randomized), relatives and friends (8.9% consented, 11.3% randomized), schools (7.3% consented, 6.7% randomized), mental health clinics (6.6% consented, 5.1%randomized), newspaper ads (5.6% consented, 6.7% randomized), primary care clinics (3.0% consented, 26% randomized), social services (2.6% consented, 2.1% randomized), bus ads (17% consented, 2.1% randomized), radio ads (17% consented, 1.0% randomized), flyer/brochure (1.3% consented, 1.0% randomized), university email (1.3% consented, 2.1% randomized). Conclusions: Preliminary results support the feasibility of recruiting adolescents with co-occurring disorders to this multi-site clinical trial. Additional research is warranted to evaluate whether free treatment, establishing new referral sources to augment existing clinic sources, or other factors are important aspects of successful recruitment. Support: This work is supported in part by NIDA grants Ul0 DA15831, UlO DA13716, K24 DA022288