CLINICAL UNIT BASED RESEARCH
Developmental Biopsychiatry Research Program
DBRP Mission
The DBRP Staff |
Our primary mission is to improve the lives of children, adolescents and adults by exploring the etiology and treatment of psychiatric disorders that arise during development. This is a multifaceted research program spanning both clinical and preclinical brain sciences.
If you are interested in learning more about our technologies or current studies, see the McLean research study page for ongoing studies or call Cindy at 617-85-LEARN (617-855-3276).
If you are interested in the McLean Motion and Attention Test (M-MAT™) please visit the BioBehavioral Diagnostics Company website (biobdx.com)
We also have a detailed summary of the McLean Motion and Attention Test (M-MAT™).
Research Studies
- Effects of Emotional Maltreatment (Verbal Abuse and Witnessing of Domestic Violence) on Brain Development
- Effects of Chronic Early Stress Due to Harsh Corporal Punishment on Brain Development and Risk for Substance Abuse
- Genetic Risk Factors and Psychiatric Mediating Factors that Link Exposure to Childhood Trauma to Increased Risk for Drug Abuse
- Development of Objective Tests to Aid in the Diagnosis and Monitoring of Treatment Response in Children, Adolescents and Adults with ADHD
- Assessing the Value of a Feedback Training Device for Improving School Performance of Children with ADHD
- Neurobiology of Adolescent Depression
- Adolescent Brain Development
Research Support
- National Institute of Mental Health (NIMH)
- National Institutes of Health (NIH)
- National Alliance for Research on Schizophrenia and Depression (NARSAD)
Donor Support
- Hall-Mercer Foundation (1988-1991)
- Snider Family (1988-1991)
- Callaghan Family – NARSAD (2001-2003)
- Simches Family (current)
Personnel
- Martin Teicher, M.D., Ph.D. - Director, and Director of the Laboratory of Developmental Neuropharmacology
- Susan L. Andersen, Ph.D. - Associate Director Preclinical Studies DBRP, and Chief, Laboratory of Developmental Neuropharmacology
- Cynthia E. McGreenery - DBRP Administrator
- Ann M. Polcari, R.N., Ph.D. - Associate Director Clinical Studies DBRP
- Carl M. Anderson, Ph.D. - Assistant Psychobiologist DBRP and Brain Imaging Center
- Majed Ashy,Ph.D. - Postdoctoral Fellow, DBRP, and Boston University Psychology Department Lecturer
- Mary Foley, R.N., M.S.C.S. - Research Associate
- Nikos Fourligas, Ph.D. - Research Associate
- Dennis M. Kim, M.D. - Assistant Psychiatrist
- Charles S. Mirabile, M.D. - Clinical Investigator
- Carryl P. Navalta, Ph.D. - Assistant Psychologist
- Kyoko Ohashi, Ph.D. - Postdoctoral Research Fellow
- Jacqueline Samson-Jian, Ph.D. - Associate Psychologist, Chief Depression Research Facility
- Frederic Schiffer, M.D. - Clinical Investigator
- Akemi Tomoda, M.D., Ph.D. - Research Scientist
- Elizabeth A. Valente, M.A. - Clinical Research Assistant and Activity Therapist
- Paul Wender, M.D. - Senior Consultant
DBRP Collaborators
- Yvonne Sparling, Ph.D. - Director, Clinical Services, Massachusetts Department of Youth Services
Former Students and Trainees
Ongoing Studies
- Differential Effects of Exposure to Parental Verbal Aggression and Witnessing of Domestic Violence on Brain Morphology, Functional Activity and Neurochemistry
- Effects of Harsh Corporal Punishment on Brain Morphology, Functional Activity and Neurochemistry
- Effects of Harsh Corporal Punishment on Physiology and Neuroendocrinology of Stress Response
- Genetic Risk Factors and Psychiatric Mediating Factors that Link Exposure to Childhood Trauma to Increased Risk for Drug Abuse
- Development of Objective Tests to Aid in the Diagnosis of ADHD in Children, Adolescents and Adults
- Functional Brain Activity in Adolescent with Depression
- Preclinical Studies of Adolescent Brain Development
Technologies Used in Our Studies
- Functional Magnetic Resonance Imaging T2-relaxometry
- Morphometric Brain Imaging and Image Analysis
- Diffusion Tensor Imaging
- Magnetic Resonance Spectroscopy
- Optical Oximeter Brain Activity Measurements
- Infrared Motion Analysis
- Computerized Measures of Attention and Attention-State Shifts
- Actigraphy and Chronobiological Measures
- Trier Social Stress Test with Measures of Stress Hormones and Heart Rate Variability
- Spectral and Wavelet Analyses of Multisecond Oscillations in Physiologial Systems
See the McLean Research study page for these and other clinical trials at McLean.