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MAILMAN RESEARCH CENTER

Neurostatistics Laboratory

The Neurostatistics Laboratory
Fig 3: Automatic segmentation of digital images of Fos expression in rat brain for the identification, counting and spatial pattern detection of Fos-positive nuclei. Non-Fos candidate objects shown are readily excluded by our mathematical morphology algorithm that employs darkness, size and shape criteria automatically after training, together with statistical optimization. As shown, the present method works well with various types of background contrast and staining patterns.
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